Developing a safer test for joint and bone infections in children

Māori and Pacific children have more frequent bone and joint infections than other children. This study aims to develop a new technique to detect bacterial infection inside children’s bones and joints without having to use invasive tests (e.g. using a needle to withdraw fluid from a joint).

Dr Amy Scott-Thomas will test a new method using magnetic beads to recognise and concentrate specific fragments of bacterial DNA found in samples of blood and urine, and therefore enable sensitive detection of the bacteria.

If the study is successful, it will reduce stress for children by avoiding needles and other invasive tests, and enable faster diagnosis and treatment with antibiotics. This should also help to avoid development of antibiotic-resistant bacteria by incorrect prescribing.