Acute respiratory illnesses are the leading cause of death in New Zealand children. The umbrella term of respiratory conditions includes bronchiectasis, pneumonia, asthma and cystic fibrosis.
Bronchiectasis Exacerbation Study (BEST)
A study to determine whether antibiotics are necessary to treat bronchiectasis when chest physiotherapy may be effective with viral infections and which is the most effective antibiotic to use.
Can a novel intervention improve quality of life for children with sleep problems?
Testing the efficacy of a mandibular advancement splint in children who suffer from sleep-disordered breathing, in order to prevent further health issues developing in the future.
Can probiotics provided to mothers improve the health of their children?
Gaining a greater understanding of the effects of probiotics on the function and composition of organisms in the gut of children, and the role this plays in presence of eczema.
Early detection of bacteria in the lungs using a non-invasive breath test?
Laboratory analysis of mucus build up in the cystic fibrosis lung to determine an effective breath testing diagnostic of harmful bacteria.
Novel treatments to treat antibiotic-resistant Staphylococcal skin infections
In the presence of ferrous iron, vitamin C-based antibiotic creams can be resensitised to kill the superbug staphylococcus aureus (SA). This project will repurpose anti-aging creams to kill SA.
An oxygenated solution to pneumonia deaths in Pacific children
A pilot project in Tonga to test and refine a 24/7 portable oxygen system, with limited or absence of power, in reducing pneumonia-related child mortality.
A quest to find new antibiotics to fight superbugs
This project, stemming from a seed grant last year, is investigating New Zealand microorganisms from plants to as to their ability to kill the bug staphylococcus aureus.
A randomised controlled trial (RCT) using sildenafil aiming to improve the outcomes of babies with slowed growth in the womb
Intrauterine growth restriction (IUGR) can result in severe health complications and currently has no treatment. This study will seek to improve the growth of these vulnerable infants.